Treatment with an immature dendritic cell-targeting vaccine supplemented with IFN-α and an inhibitor of DNA methylation markedly enhances survival in a murine …

JT Gordy, K Luo, A Kapoor, ES Kim, SK Ayeh… - Cancer Immunology …, 2020 - Springer
… The chemokine MIP-3α (CCL20) binds to CCR6 on immature … in developing vaccine-derived
anti-tumor immunity in preclinical … The addition of more tumor associated antigens and/or …

Targeting tumor-associated macrophages to increase the efficacy of immune checkpoint inhibitors: a glimpse into novel therapeutic approaches for metastatic …

C Ceci, MG Atzori, PM Lacal, G Graziani - Cancers, 2020 - mdpi.com
… in the failure of the anti-tumor immune surveillance, as well … ; IL-10 and glucocorticoids can
elicit the M2c form of active … complex, impairing effector T-cell-mediated responses to tumor …

Development and characterization of immunogenic genetically engineered mouse models of pancreatic cancer

LJ Lambert - 2020 - dspace.mit.edu
… the immune system can be mobilized to elicit anti-tumor … our current understanding of the
anti-tumor immune response. … of antigen-expressing cancer cells by effector T cells, which in …

A chemokine-fusion vaccine targeting immature dendritic cells elicits elevated antibody responses to malaria sporozoites in infant macaques

K Luo, JT Gordy, F Zavala, RB Markham - Scientific reports, 2021 - nature.com
… on the protective efficacy in a mouse challenge model of a vaccinevaccine construct
has two functions: (1) to target the vaccine antigen to the C–C Motif Chemokine Receptor 6 (CCR6) …

[引用][C] Antibody-based approaches to modulate immune response

A Segués Cisteró - 2023 - Utrecht University